Journal article
The sit-to-stand test as a patient-centered functional outcome for critical care research: a pooled analysis of five international rehabilitation studies
HK O'Grady, L Edbrooke, C Farley, S Berney, L Denehy, Z Puthucheary, ME Kho
Critical Care London England | Published : 2022
Abstract
BACKGROUND: With ICU mortality rates decreasing, it is increasingly important to identify interventions to minimize functional impairments and improve outcomes for survivors. Simultaneously, we must identify robust patient-centered functional outcomes for our trials. Our objective was to investigate the clinimetric properties of a progression of three outcome measures, from strength to function. METHODS: Adults (≥ 18 years) enrolled in five international ICU rehabilitation studies. Participants required ICU admission were mechanically ventilated and previously independent. Outcomes included two components of the Physical Function in ICU Test-scored (PFIT-s): knee extensor strength and assist..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
Authors:MEKholds a Canada Research Chair in Critical Care Rehabilitation and Knowledge Translation from the Canadian Institutes of Health Research (CIHR).Primary Studies:I-SURVIVE-Canadian Respiratory Health Professionals grant from the Lung association and Ontario Ministry of Research, Innovation, and Science Early Researcher Award.TryCYCLE-Canadian Institutes of Health Research and Institute of Musculoskeletal Health, Arthritis Operating grant-Priority Announcement and IMHA New investigators-Bridge Funding (131584).CYCLE Pilot RCT-Technology Evaluation in the Elderly Network Catalyst (now Canadian Frailty Network; CAT2014-05), Canadian Respiratory Research Network Emerging Research Leaders Initiative, Ontario Thoracic Society Grant-in-Aid and Canadian Institutes of Health Research Transitional Operating Grant (Award #142327), Canada Foundation for Innovation, Ontario Ministry of Research and Innovation and Restorative Therapies (Baltimore, MD) provided 2 RT-300 supine cycle ergometers for Toronto General Hospital and London Health Sciences sites.eStimCycleNational Health and Medical Research Council of Australia, Mrs. Sheila S. Pakula and Dr Lawrence C. Pakula Patient Recovery Fund in Pulmonary and Critical Care Medicine at Johns Hopkins University, The American Thoracic Society Foundation Unrestricted Research Grant, Intensive Care Foundation of Australia and Austin Health Medical Research Fund and Restorative Therapies provided the RT-300 supine cycle ergometer to the Austin Health site.EXERCISE-NHMRC (Grant 454717), Physiotherapy Research Foundation, the Austin Hospital Medical Research Foundation and Australian and New Zealand Intensive Care Society.